Nina Simone's "Don't Smoke in Bed" is about a woman leaving her cheating husband. When she says 'Don't Smoke in Bed' she is singing about knowing her husband is cheating on her. Most likely, she knows he smokes in bed after sex and has found some evidence to confirm her suspicions. Her voice carries a tinge of disappointment, regret, bitterness and anger. When I hear the song, I'm reminded that trust is precious and vulnerable, and can easily "go up in smoke".